Postdoctoral Associate in Immunology and Immunotherapy of Cancer and Viral Infections

Health Research Inc. (HRI) Roswell Park Division
Full Time
Commensurate with relevant research experience and NIH pay scale
Description of Duties

The laboratory of Dr. Pawel Kalinski in the Department of Immunology is looking for a postdoctoral candidate to work on a research project evaluating the role of dendritic cells, NK cells and T cells in the development of immunity against cancer and viral infections.  The goal of the project is to develop novel treatments of acute and chronic viral infections, premalignant states and cancer. The selected individual will perform studies in human in vitro models, human ex vivo tissue explant culture models (and potentially mouse in vitro and in vivo models) to study the impact of viruses and mediators of viral infections, hypoxia and cancer metabolites  upon human cancer and epithelial cells, and the resulting activation of dendritic cells, antigen uptake and presentation to T cells.  The experiments will involve the analyses of the underlying molecular pathways, immune cell functions and may involve mouse models of cancer. The incumbent will be involved in preparation of scientific manuscripts and grant applications, with the expectation of writing first author papers and contributing to papers of other members of the team.


The candidate should have a Ph.D. (in immunology, virology or a related field), MD or MD/PhD, and prior experience with commonly used laboratory methods and in vitro models to study the impact of viruses and virally-induced inflammatory products on dendritic cells, T cells and/or epithelial (including cancer) cells. Expertise in cancer immunology or general experience in immunotherapy (vaccines, adjuvants) and related assays is desirable. The candidate must be able to work independently, develop and carry out several scientific projects simultaneously, possess strong interpersonal and scientific writing skills, and have a proven track record of publication in the relevant areas.

Applicant Instructions

Interested applicants are invited to submit 1) letter highlighting research interests and career goals, 2) curriculum vitae and 3) contact details for three (3) references to:
Dr. Tina Amyes, Scientific Program Manager at