Post-doctoral Fellowship in Cancer Metabolism, Transcription and Metastasis Research

Company
Health Research Inc. (HRI) Roswell Park Division
Department
Cell Stress Biology
Hours/Shift
Full Time/Days
Salary
Commensurate with accumulated post doctoral research and NIH pay scale
Description of Duties

Postdoctoral position is open for highly motivated candidates in the laboratory of Dr. Subhamoy Dasgupta at the Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, NY- a National Cancer Institute (NCI) designated comprehensive cancer center. The Dasgupta lab focuses on discovering novel tumor metabolic adaptations, and investigates associated biological mechanisms such as transcriptional regulation, nuclear receptor and steroid hormone action, nutrient signaling, mitochondrial biology, epigenetics, and tumor immunology in the progression of cancer metastasis (Sawant Dessai A, et al, Under Review, 2020; Dasgupta S, et al, Nature, 556, 249–254, 2018; Dasgupta S, et al, Journal of Clinical Investigation, 125(3):1174-88, 2015).

State of art facilities such as proteomics, genomics, and metabolomics along with molecular biology techniques are widely used in the laboratory. Multiple models systems, including Genetically Engineered Mouse Models (GEMMs), patient-derived xenograft (PDX), and syngeneic tumor models are used to address challenging mechanisms in breast and prostate cancer progression and metastasis. Currently the laboratory is stably funded by multiple grants from NIH/NCI, Susan G. Komen Breast Cancer Foundation, and other funding sources.

Qualifications

The search is primarily targeted towards scientists who are completing their PhD or have recently graduated with first author publications demonstrating their skills in any related areas of gene transcription, epigenetics, biochemistry, cancer biology, and immunology. Experience of working with mouse models of cancer will be preferred. The candidate should possess outstanding written and verbal communication skills.

Applicant Instructions

To apply, please send a cover letter highlighting your past research experience, career goals and research interests, and CV to Dr. Subhamoy Dasgupta at Subhamoy.Dasgupta@RoswellPark.org