Post-doctoral Fellow in Myeloma

Company
Health Research Inc. (HRI) Roswell Park Division
Department
Department of Medicine
Hours/Shift
Full Time/Days
Salary
Commensurate with accumulated post doctoral research and NIH pay scale
Description of Duties

The Multiple Myeloma/Amyloidosis Service of the Department of Medicine is seeking a full-time Postdoctoral Fellow in the laboratory of Dr. Jens Hillengass. The Hillengass lab focuses on the spatial heterogeneity of bone marrow infiltration of multiple myeloma. Using modern genomic DNA and RNA sequencing approaches as well as immunological analyses Dr. Maximilian Merz was able to show genes being differentially expressed in osteolytic lesions compared to the random bone marrow. Longitudinal samples showed transcriptional changes after treatment (Merz, M, et al, Annual Meeting of the American Society of Hematology, 2020; Manuscript in preparation). Furthermore, the group works on the utilization of modern imaging techniques for early detection of monoclonal plasma cell disorders and to analyze treatment response. Further projects deal with the influence of interventions like physical exercise and nutrition on the immune system and immunosurveillance in patients with monoclonal plasma cell disorders.

Qualifications

The search is primarily targeted towards scientists who are completing their PhD or have recently graduated with first author publications demonstrating their skills in any related areas of gene transcription, cancer biology, and immunology. Experience with downstream analyses of whole exome sequencing and single-cell RNA sequencing data (e.g. Seurat, Monocle 3, etc.) will be preferred. The candidate should possess outstanding written and verbal communication skills.

Applicant Instructions

To apply, please send a cover letter highlighting your past research experience, career goals and research interests, and CV via email to Jens Hillengass, MD, PhD, Chief of Myeloma, Department of Medicine, Roswell Park Comprehensive Cancer Center, Jens.Hillengass@RoswellPark.org.