Stomach Cancer Research

Dr. Wen Wee Ma explains how phase 1 clinical trials lead to better treatment options for advanced gastrointestinal cancers.

Research: The Way Forward

In the past decade, Roswell Park offered 94 clinical trials for gastrointestinal cancer patients. Dr. Iyer stresses the importance of choosing a high-volume cancer center.

With a robust research program, Roswell Park pioneers more effective treatments and prevention measures, providing patients with more options to maximize their chance for a cure. An emphasis on translational research allows us to develop our discoveries in the laboratory into promising therapeutics for patients — moving from lab bench to bedside — as quickly as possible.

Some areas of current research include:

  • Novel targeted therapies: Our researchers are looking at ways to block signals between cancer cells.
  • Decreasing toxicity of current treatments: We are exploring ways to make existing treatment more tolerable, such as by evaluation of specific genetic changes that are associated with increased risk of side effects.
  • Non-invasive methods to predict response: Patient response to treatment is evaluated using methods such as the CellSearch System, which measures circulating tumor cells and other tests to predict a patient’s response or resistance to therapy.

Investigative Approaches

Any new treatment undergoes years, even decades, of study and clinical studies, which involve people, encompass the final phases of cancer treatment research. Participating in a clinical study may be an important treatment option for many patients, who may be among the first to benefit from a new drug or therapy. About 50 percent of our patients are eligible for a clinical study. Whether or not you choose to participate is entirely your choice.