Pediatric Clinical Trials

  • Matthew Barth, MD and young adult cancer patient.

At Roswell Park Oishei Children’s, our patients can take part in clinical trials that are designed for children with cancer and blood disorders. Our physicians are both involved in and leaders of national studies in the NCI-sponsored Children’s Oncology Group. The following investigators lead their respective fields and bring their expertise directly to our patients at Roswell Park Oishei Children’s:

  • Dr. Clare Twist is an international expert in pediatric neuroblastoma.
  • Dr. Matthew Barth offers cutting-edge research for pediatric lymphomas.
  • Dr. Kara Kelly oversees the design and implementation of new therapies for Hodgkin lymphoma as the chair of the committee.

We also offer clinical trials through collaborations with other cancer centers and other organizations, such as the Dana-Farber Cancer Institute/ALL Consortium. This gives our patients the chance to receive the newest breakthrough treatments for childhood cancer.

Clinical trials are studies designed to evaluate promising new medical treatments for cancer and other illnesses and learn how well and safely they work. While taking part in clinical trials may have risks, these experimental treatments could one day become the standard of care for our future patients who are diagnosed with cancer and other diseases. Clinical trials can also offer new treatment choices for patients who have not had success with traditional therapies.

Experimental Therapeutics Program

The new Experimental Therapeutics Program, led by Dr. Clare Twist gives our pediatric patients access to novel therapies they can try only through early-phase clinical trials. Many clinical trials for adult Roswell patients are now available to our pediatric, adolescent and young adult patients. This means your child can have experimental cancer treatment right here in our facility.

Our patients who needed to take part in pediatric clinical trials used to have to travel to New York City, Pittsburgh, Cincinnati or beyond. We are excited that our patients can now access early-phase clinical trials right here in upstate New York. This keeps your child closer to his or her family, support system and care team.

Our Experimental Therapeutics Program also partners with pharmaceutical drug companies and groups that are dedicated to studying new medicines and therapies for children. This partnership gives Roswell Park the chance to help launch experimental cancer treatment studies and to possibly develop our own pediatric cancer therapeutics to study in a clinical trial format.

Dana-Farber Cancer Institute/ALL Consortium

Roswell Park Oishei Children’s is a partner with the Dana-Farber Cancer Institute/ALL Consortium, which offers clinical trials for children diagnosed with Acute Lymphoblastic Leukemia (ALL). This Consortium includes seven collaborating institutions that identify newly diagnosed pediatric patients for treatment. The results are outstanding: patients receiving clinical trials through the Consortium have a five-year event-free survival rate of more than 86 percent and above 90 percent for standard risk groups.

At Roswell Park Oishei Children’s, we are proud to offer our ALL cancer patients access to these clinical trials through the Consortium. Dr. Kara Kelly spearheads this partnership for our facility; we are the only Consortium member in New York State outside of the metropolitan New York City area.

Clinical Trial Resources

Making the decision for your child to take part in a clinical trial can be a challenge, both emotionally and mentally. These resources may help as you learn more about the clinical trial process at Roswell Park:

Contact Us

To learn more about taking part in a pediatric clinical trial through Roswell Park Comprehensive Cancer Center, please call 1-800-ROSWELL (1-800-767-9355) or email askrpci@roswellpark.org.