Alex Adjei, MD, PhD, FACP

Alex Adjei, MD, PhD, FACP

Roswell Park Cancer Institute
Professor and Chair, Department of Medicine
Senior Vice President of Clinical Research
The Katherine Anne Gioia Chair in Cancer Medicine
State University of New York at Buffalo
Academic Scholar in Medicine
School of Medicine and Biomedical Sciences

Alex Adjei, MD, PhD, joined the faculty of Roswell Park Cancer Institute (RPCI) in 2006 as Senior Vice President of Clinical Research and Katherine Anne Gioia Chair of Cancer Medicine. Dr. Adjei is responsible for expanding the Department’s phase I and Thoracic Oncology programs and strives to enhance existing programs and establish new clinical and research initiatives.

Dr. Adjei is a distinguished national leader in translational research, drug development and thoracic oncology. He joined RPCI from the Mayo College of Medicine, Rochester, MN, where he served as Professor of Oncology and led highly successful thoracic oncology and Phase I clinical research programs.

Dr. Adjei earned his medical degree from the University of Ghana Medical School in Legon. He obtained a doctorate in pharmacology at the University of Alberta in Edmonton, Canada. Dr. Adjei completed residency training at Howard University, Washington, DC, and clinical and research fellowships in oncology at Johns Hopkins School of Medicine, Baltimore, MD. He is a Diplomate of the American Board of Internal Medicine.

Dr. Adjei’s research is focused on assessing the toxicity, pharmacology and initial activity of novel agents for the therapy of solid tumors and developing biomarkers of drug effects. His laboratory studies focus on elucidating mechanisms of action and resistance of novel agents that inhibit cell signaling. He also conducts phase II clinical trials of novel agents in lung cancer.

In recognition of his long track record in oncology drug development, Dr. Adjei was recognized in 2012 as the first recipient of the American Society of Clinical Oncology (ASCO) Drug Development Research Professorship. This award has allowed him to focus a significant portion of his time in mentoring junior faculty, both from the U.S. and internationally, in the areas of drug development, clinical trial design and regulatory science.

Dr. Adjei is an active member of numerous professional organizations. As a member of the American Association for Cancer Research (AACR), he has served on numerous committees. He was Chair of the Minorities in Cancer Research Council and co-Chair of the AACR’s 2005, 2007 and 2012 Annual Meetings. He has served on ASCO’s annual meeting program committee twice and has been a member of the Translational Research Task Force, Cancer Research Committee and Grants Selection Committee. He is a member of the Board of Directors of the International Association for the Study of Lung Cancer (IASLC).

Dr. Adjei also has served on many committees for the National Cancer Institute (NCI). He has served as Group Vice Chair of the NCI’s North Central Cancer Treatment Group (NCCTG), from 2005 to 2007, and as Lung Committee Chair of that group from 2005 to 2012). He is currently a member of the NCI’s Thoracic Malignancies Steering Committee and Vice Chair of its Lung Intergroup Correlative Science Committee. He was a member of the Lung Cancer Progress Review Group in 2000 and the Lung Cancer Concept Evaluation Panel from 1999-2002. He has served on several National Institutes of Health (NIH) committees as well, having chaired a Clinical and Translational Science Awards (CTSA) Study Section from 2007-2012, and is a member of the NCI Clinical Oncology (CONC) and Initial Review Group (IRG) Subcommittee A – Cancer Centers study sections. He continues in his senior leadership role in lung cancer nationally as a legacy Respiratory Program Chair of the newly constituted cooperative group Alliance for Clinical Trials in Oncology (ACTION).

Dr. Adjei has authored or co-authored 200 peer-reviewed manuscripts and over 200 abstracts, two books and 15 book chapters. He has several editorial positions on academic journals. He is Associate Editor of the American Journal of Clinical Oncology and Editor-in-Chief of Journal of Thoracic Oncology.

Areas of Expertise: 
Lung cancer
Special Interests: 
Drug Development (Phase I clinical trials; Phase II clinical trials)
Assessing toxicity, pharmacology and initial activity of novel agents for solid tumors
Development of biomarkers of drug effects
Mechanism of action and resistance of novel agents that inhibit cell signaling
Pharmacogenetics
Board Certification: 
Diplomate, Internal Medicine, American Board of Internal Medicine
Medical Oncology, American Board of Internal Medicine
Fellowship: 
Johns Hopkins School of Medicine, Baltimore, MD
Residency: 
Howard University, Washington, DC
Education and Training: 
MD - University of Ghana Medical School, Legon, Ghana
PhD - University of Alberta, Edmonton, Alberta, Canada