Mihai Merzianu, MD

Assistant Professor

Department of Pathology & Laboratory Medicine

Roswell Park Cancer Institute

Assistant Professor of Pathology & Anatomical Sciences

School of Medicine and Biomedical Sciences, State University of New York at Buffalo

Profile

Areas of Expertise:

Leukemia

Lymphoma

Salivary gland cancer

Squamous cell carcinoma and precursor lesions

Thyroid tumors

Research

Research Interests:

Identifying markers for early detection, prognostic stratification and accurate classification of head and neck cancer and precursor lesions

Thyroid neoplasms of follicular origin

Prognostic markers and classification of acute myeloid leukemia and B-cell neoplasms

Selected Publications:

Background Information

Education and Training:

MD - University of Medicine, Timisoara, Romania

Residency:

St Luke's-Roosevelt Hospital Center, Beth Israel Hospital, New York, NY

Board Certification:

Anatomic Pathology, American Board of Pathology

Clinical Pathology, American Board of Pathology

Hematology, American Board of Pathology

Fellowships:

Memorial Sloan-Kettering Cancer Center, New York, NY

MD Anderson Cancer Center, University of Texas, Houston, TX

Publications

Publications:

Kanehira K, Merzianu M. HMGA2 nuclear expression in thyroid tissue is restricted to neoplastic lesions and is associated with a malignant phenotype. Laboratory investigation 2010; 90(Suppl. 1):128A
Ali L , Cheney R , Merzianu M. Subclinical chronic lymphocytic leukemia with atypical cutaneous presentation. Journal of cutaneous pathology 2011; 38(2):236-240
Malik DA , Starostik P , Deeb G , Risch N, Barcos M , Merzianu M. Comparative assessment of zinc-based fixatives in hematopathology practice. American journal of clinical pathology 2010; 134(4):58
Merzianu M , Khoury T. Gastrointestinal signet-ring cell carcinoma vs metastatic lobular carcinoma to gastrointestinal tract: an immunohistochemical differential diagnostic strategy. American journal of clinical pathology 2010; 134(4):59
Jayaprakash V, Bogaards A, Frustino J, Gill SR, Wilson BC, Mang TS, Hutson AD, Marshall JR, Johnson T, Ramananda S, Moysich KB, Popat SR, Loree TR, Rigual NR, Merzianu M, Sullivan M, Reid ME. Autofluorescence-guided surveillance for oral cancer. Cancer prevention research (Philadelphia, Pa.) 2009; 2(11):966-974
Seshadri M, Merzianu M, Tang H, Rigual NR, Sullivan M, Loree TR, Popat SR, Repasky EA, Hylander BL. Establishment and characterization of patient tumor-derived head and neck squamous cell carcinoma xenografts. Cancer biology and therapy 2009; 8(23):2275-2283
Tezal M, Wactawski-Wende J, Lillis C, Hauck L, Merzianu M, Rigual NR, Loree TR, Reid ME, Stoler D, Marshall JR, Hyland A, Sullivan MA, Scannapieco FA. Chronic periodontitis and the incidence of head and neck squamous cell carcinoma. Cancer epidemiology, biomarkers and prevention 2009; 18(9):2406-2412
Durie N, Merzianu M. Benign Signet Ring-Like Cells in Follow-Up Biopsies of Patients with Gastric Lymphoma in Remission - A Rare but Significant Diagnostic Pitfall. Laboratory investigation 2011; 91(Suppl. 1):617
Minca EC, Jean-Charles G, Merzianu M. HGMA2 Is Overexpressed in Epithelial Precursor Lesions and Oral Squamous Cell Carcinoma. Laboratory investigation 2011; 91(Suppl. 1):1194
Platek ME, Merzianu M, Mashtare TL, Popat SR, Rigual NR, Warren GW, Singh AK. Improved survival following surgery and radiation therapy for olfactory neuroblastoma: analysis of the SEER database. Radiation oncology (London, England) 2011; 6:41
Syriac S, Sait S, Cheney RT, Merzianu M. FLI1 and CD57 Expression in Round Cell Sinonasal Tumors. Laboratory investigation 2011; 91(Suppl. 1):1206
Rigual NR, Cheney RT, Iwenofu OH, Li Q, Loree TR, Popat SR, Merzianu M. Idiosyncrasies of scalp melanoma. Laryngoscope 2007; 117(8):1354-1358
Solomon LW, Merzianu M, Sullivan M, Rigual NR. Necrotizing sialometaplasia associated with bulimia: case report and literature review. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2007; 103(2):e39-e42
Malin BT, Merzianu M, Cherr GS, Thankappan K, Rigual NR. Acute carotid rupture associated with postoperative Staphylococcus Aureus infection. Laryngoscope 2011; 121(Suppl. 5):S288
Higgs DE, Bogner PN, Hicks DG, Starostik P, Wilding GE, Mashtare TL, Merzianu M. Oligo- and polyclonal B cell response to lung carcinoma is common. Laboratory investigation 2007; 87(Suppl. 1):1486
Platek ME, Mashtare TL, Popat SR, Merzianu M, Singh AK. Improved Survival following Surgery and Radiation for Olfactory Neuroblastoma: Analysis of the SEER Database. International journal of radiation oncology, biology, physics 2009; 75(3 Suppl.):S396
Jayaprakash V, Reid M, Hatton E, Merzianu M, Rigual N, Marshall J, Gill S, Frustino J, Wilding G, Loree T, Popat S, Sullivan M. Human papillomavirus types 16 and 18 in epithelial dysplasia of oral cavity and oropharynx: a meta-analysis, 1985-2010. Oral oncology 2011; 47(11):1048-1054
Minca EC, Popat SR, Chadha MK, Merzianu M. Small lymphocytic lymphoma obscuring microscopic tonsillar squamous cell carcinoma: an unknown occurrence with a known primary. Head and neck pathology 2012; 6(1):125-129
Wang ES, Agwa E, Zhang SX, Merzianu M. Acute Leukemias of Ambiguous Lineage: The Roswell Park Experience. Blood 2011; 118(21):1092
Merzianu M, Wallace PK. Case study interpretation--Portland: Case 4. Acute leukemia of ambiguous lineage, unclassifiable. Cytometry. Part B, Clinical cytometry 2012; 82B(3):186-191
Ali L, Cheney R, Merzianu M, Chen F. Leukemia cutis as the initial presenting sign of systemic chronic lymphocytic leukemia, an easily missed diagnosis. Journal of cutaneous pathology 2009; 36(1):123