Research & Education
Platinol, platinum (There may be other brand names for this medication.)
How is it Administered?
Your medicine will be injected into a vein (intravenously /IV. Typically, the infusion will take approximately 7 hours, which includes having IV fluids before and after the cisplatin and medication to prevent/lessen nausea. (Plan on spending the entire day at the Chemoinfusion Center.)
How Does Cisplatin Work?
Cancer is a group of diseases in which abnormal cells divide without control. Both normal and cancer cells go through cycles (resting phase, active growing phases, and division/reproduction). Your chemo schedule is based upon your cancer type, how fast the cancer cells divide, and when each drug is the most likely to be effective. This is why chemotherapy is typically given in cycles.
Cisplatin is in a class of drugs known as platinum-containing compounds (metal salt) and it is an alkylating agent. It works against the cancer cells while they are in the “resting phase” and slows or stops the cells’ growth.
The faster cells reproduce, the more likely it is that chemotherapy will damage and/or kill them. Since there are some types of cells in your body that naturally reproduce rapidly, these types of cells are likely to be damaged/destroyed by chemo. These normal cells will eventually grow back and be healthy. During treatment, however, you may experience side effects involving the cells that line the digestive tract (mouth, stomach, and intestines), the hair follicles, and bone marrow.
What Is Cisplatin Used For?
This drug is used to treat many cancers including cancers of the bladder, ovary, testicles, head and neck, and cervix, as well as mesothelioma, and non-small cell lung cancer (NSCLC).