Nathalie Zeitouni, MDCM, FRCPC

Associate Professor
Chief, Dermatologic Surgery
Interim Chair
Department of Dermatology
Roswell Park Cancer Institute
Fellowship Director
American College of Mohs Surgery

Profile

Areas of Expertise: 
Mohs micrographic Surgery
Dermatofibrosarcoma protuberans
Extramammary Paget’s disease
Melanoma
Merkel cell carcinoma
Sebaceous carcinoma
Skin cancer in organ transplant recipients
Biography: 

Dr. Nathalie C. Zeitouni is a fellowship trained Mohs surgeon who joined the staff of Roswell Park Cancer Institute in 1997, as Chief of Dermatologic Surgery and Director of the Pigmented Lesion Clinic. She earned her medical degree at McGill University, Montreal, Canada in 1993. She completed residency training in Dermatology at Laval University, Quebec City, (1996), and a fellowship in Mohs Micrographic Surgery at the University of Alabama, Birmingham, AL (1997).

Dr. Zeitouni is licensed by New York State and Alabama and is certified by the American Board of Dermatology (1997), Royal College of Physicians of Canada (1997), and the College of Specialists of the Providence of Quebec (1997). She is also Interim Chair, Associate Professor of Dermatology and Director of Dermatologic Surgery Training at the University at Buffalo School of Medicine and Biomedical Sciences. She is the Mohs Surgery Fellowship Director since 2004.

Dr. Zeitouni’s research interests focus on extramammary Paget’s disease; Merkel cell carcinoma and skin cancers in organ transplant patients. She is part of Merkel cell carcinoma Multicenter Interest Group (MMIG) and International Transplant Skin Cancer Collaborative (ITSCC). Her interests also include determining risk factors and developing treatment guidelines for certain rare skin cancers tumors. In 2008, Dr. Zeitouni assumed the role of Director of Photodynamic Therapy (PDT) in Clinical Dermatology.

Dr. Zeitouni is a member of the American Academy of Dermatology, Royal College of Physicians and Surgeons of Canada, American College of Mohs Micrographic Surgery and Cutaneous Oncology, American Academy of Cosmetic Surgery, International Society for Dermatologic Surgery, European Academy of Dermatology and the Buffalo-Rochester Dermatologic Society.

She has authored and co-authored many journal articles and book chapters. She presents abstracts both on a national and international level.

Research

Research Interests: 
Risk factors and treatment guidelines for rare skin cancers
Photodynamic therapy for skin cancers
Management of high risk tumors

Background Information

Education and Training: 
MD - McGill University Faculty of Medicine, Montreal, QC, Canada
Residency: 
Laval University (Dermatology) Quebec City, QC, Canada
Board Certification: 
Dermatology, American Board of Dermatology
Royal College of Physicians of Canada
Fellowships: 
University of Alabama (Mohs’ Micrographic Surgery) Birmingham, AL

Publications

Publications: 
  • Meguerditchian A-N, Wang J, Lema B, Kraybill WG, Zeitouni NC, Kane JM. Wide excision or Mohs micrographic surgery for the treatment of primary dermatofibrosarcoma protuberans. American journal of clinical oncology 2010; 33(3):300-303
  • Najarian DJ, Morrison C, Sait SNJ, Meguerditchian AN, Kane III J, Cheney R, Zeitouni NC. Recurrent giant cell fibroblastoma treated with Mohs micrographic surgery. Dermatologic surgery 2010; 36(3):417-421
  • Zwald FO, Otley CC, Euvrard S, Proby CM, Brown MD, Patel MJ, Bordeaux J, Ratner D, Zeitouni NC, Billingsley EM, Christenson LJ, Stasko T. Melanoma in solid organ transplant recipients. American journal of transplantation 2010; 10(5):1297-1304
  • Najarian DJ, Packianathan V, Zeitouni NC. Annular leukocytoclastic vasculitis associated with sorafenib administration. Journal of drugs in dermatology : JDD 2010; 9(6):697-698
  • Housel JP , Izikson L , Zeitouni NC. Noninvasive extramammary Paget's disease treated with photodynamic therapy: case series from the Roswell Park Cancer Institute. Dermatologic surgery 2010; 36(11):1718-1724
  • Izikson L , Nornhold E , Iyer JG , Nghiem P , Zeitouni NC. Merkel cell carcinoma associated with HIV: review of 14 patients. AIDS (London, England) 2011; 25(1):119-121
  • Izikson L , Seyler M , Zeitouni NC. Prevalence of underdiagnosed aggressive non-melanoma skin cancers treated with Mohs micrographic surgery: analysis of 513 cases. Dermatologic surgery 2010; 36(11):1769-1772
  • Lemos BD , Sober AJ , Gershenwald JE , Sondak VK , Byrd DR , Zeitouni NC , Yu SS , Ross MI , Paulson KG , Otley CC , Liegeois-Kwon NJ , Johnson TM , Fang LC , Bichakjian CK , Phillips JL , Iyer JG , Storer BE , Nghiem P. Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: analysis of 5823 cases as the basis of the first consensus staging system. Journal of the American Academy of Dermatology 2010; 63(5):751-761
  • O'Neill J, Fien S, Zeitouni NC. ALA-PDT for the treatment of cutaneous pseudolymphoma: a case report. Journal of drugs in dermatology : JDD 2010; 9(6):688-689
  • Ramsdell AM, Zeitouni N. Long-term follow-up of a hemifacial lentigo maligna treated using 5% imiquimod. Dermatologic surgery 2009; 35(2):287-290
  • Zhan FQ, Packianathan VS, Zeitouni NC. Merkel cell carcinoma: a review of current advances. Journal of the National Comprehensive Cancer Network : JNCCN 2009; 7(3):333-339
  • Zeitouni NC, Giordano CN, Kane JM. In-transit merkel cell carcinoma treated with isolated limb perfusion or isolated limb infusion: a case series of 12 patients. Dermatologic surgery 2011; 37(3):357-364
  • Fu T, Zeitouni NC, Vitolins MZ, Linos E, Larson J, Feldman D, Manson JE, LeBlanc E, Tang JY, Stefanick ML. Calcium plus vitamin D supplementation and the risk of nonmelanoma and melanoma skin cancer. Journal of investigative dermatology 2011; 131(Suppl. 1):208
  • Kitagawa KH, Bogner P, Zeitouni NC. Photodynamic Therapy with Methyl-Aminolevulinate for the Treatment of Double Extramammary Paget's Disease. Dermatologic surgery 2011; 37(7):1043-1046
  • Shabbir A, Loss L, Bogner P, Zeitouni NC. Squamous cell carcinoma developing from an epidermoid cyst of the ear. Dermatologic surgery 2011; 37(5):700-703
  • Iwenofu OH, Samie FH, Ralston J, Cheney RT, Zeitouni NC. Extramammary Paget's disease presenting as alopecia neoplastica. Journal of cutaneous pathology 2008; 35(8):761-764
  • Samie FH, Kane JM 3rd, Zeitouni NC. Repair of large abdominal defects with prostheses following Mohs micrographic surgery: case series and review of literature. Dermatologic surgery 2008; 34(3):403-406
  • Esler-Brauer L, Jaggernauth W, Zeitouni NC. Angiosarcoma developing after conservative treatment for breast carcinoma: case report with review of the current literature. Dermatologic surgery 2007; 33(6):749-755
  • Tang JY, Larson J, Zeitouni NC, Vitolins MZ, Linos E, Feldman D, Manson JE, Leblanc E, Fu T, Stefanick ML. Calcium plus vitamin D supplementation and the risk of nonmelanoma and melanoma skin cancer: post hoc analyses of the women's health initiative randomized controlled trial. Journal of clinical oncology 2011; 29(22):3078-3084
  • Iwenofu O, Cheney R, Ralston J, Zeitouni N. Extramammary paget's disease (EMPD) presenting as alopecia neoplastica. Journal of cutaneous pathology 2007; 34(1):94
  • Meguerditchian A, Lema B, Lopian S, Wang J, Kraybill WG, Zeitouni N, Kane JM. Dermatofibrosarcoma protuberans: Surgical modality, margin status, and outcome. Annals of surgical oncology 2007; 14(2 Suppl.):117-118
  • Meguerditchian A, Samie F, Vaughan M, Cheney R, Zeitouni N, Kane JM. Characterization of PDGF alpha/beta and PDGFR alpha/beta expression in dermatofibrosarcoma protuberans: Implications for targeted molecular therapy. Annals of surgical oncology 2008; 15(Suppl. 2):100-101
  • Tang JY, Spaunhurst KM, Chlebowski RT, Wactawski-Wende J, Keiser E, Thomas F, Anderson ML, Zeitouni NC, Larson JC, Stefanick ML. Menopausal hormone therapy and risks of melanoma and nonmelanoma skin cancers: women's health initiative randomized trials. Journal of the National Cancer Institute 2011; 103(19):1469-1475
  • Gamba CA, Stefanick ML, Shikany JM, Larson J, Linos E, Sims ST, Marshall J, Van Horn L, Zeitouni N, Tang JY. Low-fat dietary pattern and skin cancer risk: The Women's Health Initiative (WHI) randomized controlled dietary modification trial. Journal of investigative dermatology 2012; 132(Suppl. 1):S44
  • Jarkowski A, Hare RB, Loud P, Skitzki JJ, Kane JM, Salerno MK, Zeitouni N, Nestico J, Vona KL, Groman AE, Khushalani NI. Systemic therapy in advanced cutaneous squamous cell carcinoma (CSCC): The Roswell Park experience : ASCO Meeting Abstracts Part 1. Journal of clinical oncology 2012; 30(15 Suppl.):Abstract #e19041
  • Izikson L, Helm T, Sroa N, Zeitouni NC. Clinical stage of Merkel cell carcinoma and survival are not associated with Breslow thickness of biopsied tumor. Dermatologic surgery 2012; 38(8):1351-1356