Michael Kuettel, MD, PhD, MBA

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Professor and Chair, Department of Radiation Medicine
The Barbara C. & George H. Hyde Chair in Radiation Medicine
Roswell Park Cancer Institute
Professor and Chair of Radiation Oncology
School of Medicine and Biomedical Sciences, State University of New York at Buffalo
Clinical Director of Radiation Oncology
Kaleida Health System, Buffalo, NY

Profile

Areas of Expertise: 
Prostate Cancer

Research

Research Interests: 
Neoplastic transformation of human prostate by ionizing radiation
Practice guidelines/outcomes for patients with early-stage prostate cancer

Background Information

Education and Training: 
2002 American College of Physician Executives, CPE
1996 – 1998 Georgetown University School of Business, M.B.A.
1987 – 1989 Resident, Division of Radiation Oncology, The Johns Hopkins Hospital, Baltimore, Maryland
1985 – 1986 Resident, Internal Medicine, Northwestern Hospital, Chicago, Illinois
1983 – 1985 Graduate Medical Education, Northwestern University Medical School, Chicago, Illinois, M.D., 1985
1983 Postdoctoral Fellow, Department of Molecular Oncology, Northwestern University Medical School, Chicago, Illinois
1979 – 1983 Department of Anatomy and Cell Biology, Medical College of Wisconsin, Ph.D., 1983
Residency: 
Northwestern University Hospitals, Chicago, Illinois
Johns Hopkins Hospital, Baltimore, Maryland
Professional Experience: 
1999 – Present Professor and Chairman, Department of Radiation Medicine, Roswell Park Cancer Institute & State University of New York at Buffalo
1999 – Present Professor, Department of Molecular and Cellular Biophysics, Roswell Park Cancer Institute
1995 – 1999 Associate Professor, Department of Radiation Medicine, Georgetown University School of Medicine
1995 – 1999 Associate Professor, Department of Anatomy and Cell Biology, Georgetown University School of Medicine
1993 – 1995 Assistant Professor, Department of Anatomy and Cell Biology, Georgetown University School of Medicine
1990 – 1995 Assistant Professor, Department of Radiation Medicine, Georgetown University School of Medicine
1988 – 1989 Clinical Fellow, Division of Radiation Oncology, The Johns Hopkins Hospital
1988 – 1989 Chief Resident, Division of Radiation Oncology, The Johns Hopkins Hospital
1983 – 1985 Research Associate, Department of Cell and Molecular Biology, Northwestern University Medical School
Board Certification: 
Radiation Oncology, American Board of Radiation Oncology
Fellowships: 
Department of Molecular Oncology, Northwestern University Medical School, Chicago, Illinois
Honors and Awards: 
Fellowship – American Society for Radiation Oncology
Fellowship - American College of Radiology
Diplomate - American College of Physician Executives
Fellowship - American College of Radiation Oncology
Research and Education Scholar - Radiology Society of North America
Clinical Fellow - American Cancer Society
National Medical Student Research Award, First Place in Basic Sciences - Roche Laboratories
Excellence of Research Award - National Medical Student Research Forum
AOA Presidential Award - Northwestern University Medical School
The Teratology Society Young Investigator Award
Pre-doctoral Fellowship - American Heart Association

Publications

Publications: 
  • Mohler J, MacVicar G, Plimack ER, Pow-Sang JM, Roach III M, Rohren E, Roth BJ, Shrieve DC, Smith MR, Srinivas S, Twardowski P, Lange PH, Kuettel M, Kawachi M, Bahnson RR, Boston B, Busby JE, D'Amico A, Eastham JA, Enke CA, George D, Horwitz EM, Huben RP, Kantoff P, Walsh PC. NCCN clinical practice guidelines in oncology: prostate cancer. Journal of the National Comprehensive Cancer Network : JNCCN 2010; 8(2):162-200
  • Hurwitz M , Halabi S , Archer L , McGinnis LS , Kuettel MR , DiBiase SJ , Small EJ. Combination external beam radiation and brachytherapy boost with androgen suppression for treatment of intermediate-risk prostate cancer: long-term results of CALGB 99809. International journal of radiation oncology, biology, physics 2010; 78(3 Suppl. 1):S146
  • Lawton CA , Morton G , Kuettel M , Crook J , Baikadi M , Firat S , Gillin M , Lee WR , Yan Y , Sandler H. Long-term results of an RTOG phase II trial (00-19) of external beam radiation therapy combined with permanent source brachytherapy for intermediate risk clinically localized adenocarcinoma of the prostate. International journal of radiation oncology, biology, physics 2010; 78(3 Suppl. 1):S78-S79
  • Hurwitz MD, Halabi S, Archer L, McGinnis LS, Kuettel MR, DiBiase SJ, Small EJ. Combination external beam radiation and brachytherapy boost with androgen suppression for treatment of intermediate-risk prostate cancer: Long-term results of CALGB 99809 : 2010 Genitourinary Cancers Symposium. Journal of clinical oncology 2010; 28(15 Suppl.):Abstract #192
  • Rosenthal DI, Trotti A, Schultz CJ, Sidhu K, Kuettel MR, Garden AS, Myers JN, Ridge JA, Weber RS, Forastiere AA, Harris J, Ang KK. Early postoperative paclitaxel followed by concurrent paclitaxel and cisplatin with radiation therapy for patients with resected high-risk head and neck squamous cell carcinoma: report of the phase II trial RTOG 0024. Journal of clinical oncology 2009; 27(28):4727-4732
  • Hurwitz MD, Halabi S, Ou SS, McGinnis LS, Keuttel MR, Dibiase SJ, Small EJ. Combination external beam radiation and brachytherapy boost with androgen suppression for treatment of intermediate-risk prostate cancer: an initial report of CALGB 99809. International journal of radiation oncology, biology, physics 2008; 72(3):814-819
  • Lee WR, Greven K, Kuettel M, Baikadi M, Firat S, Morton G, Gillin M, Lawton C, Bae K, Sandler H. Late toxicity and biochemical recurrence after external-beam radiotherapy combined with permanent-source prostate brachytherapy: analysis of Radiation Therapy Oncology Group study 0019. Cancer 2007; 109(8):1506-1512
  • Malhotra HK, Avadhani JS, deBoer SF, Jaggernauth W, Kuettel MR, Podgorsak MB. Duplicating a tandem and ovoid distribution with intensity-modulated radiotherapy: A feasibility study. Journal of applied clinical medical physics 2007; 8(3):91-98
  • McCloskey SA, Kuettel MR. Counterpoint: prostate cancer life expectancy can not be accurately predicted from currently available tools. Journal of the National Comprehensive Cancer Network : JNCCN 2007; 5(7):709-713
  • Wang Z, Rajagopalan B, Malhotra HK, Kuettel MR, Podgorsak MB. The effect of positional realignment on dose delivery to the prostate and organs-at-risk for 3DCRT. Medical dosimetry 2007; 32(1):1-6
  • Yang GY, Li B, Wagner TD, Donohue KA, Flaherty L, Kuettel MR. Long-term outcome of stage I seminoma. American journal of clinical oncology 2007; 30(2):205-210
  • AL-Hussaini MH, Johnson CS, Muindi J, Chadha MK, Silliman C, Tian L, Tan W, Nesline M, Sandecki A, Kuettel MR, Mohler J, Guru K, Trump DL. Serum 25(OH) vitamin D3 response to vitamin D3 supplementation in men with prostate cancer: Results of a randomized phase II trial : ASCO Meeting Abstracts Part 1. Journal of clinical oncology 2011; 29(15 Suppl.):e13060
  • Durrani FA, Cao S, Park Y-M, Thompson G, Martin JM, Yang GY, Kuettel MR, Rustum YM. Synergistic effect of selenium compounds with radiation therapy in human A549 lung xenografts. Proceedings of the American Association for Cancer Research Annual Meeting 2007; 48:180
  • Nazareth D, Jones M, Liu J, Kuettel M, Furlani T, Podgorsak M. A distributed-computing framework using nested partitions for beam-angle optimization in IMRT. Medical physics 2007; 34(6):2403
  • Hurwitz MD, Halabi S, Archer L, McGinnis LS, Kuettel MR, Dibiase SJ, Small EJ. Combination external beam radiation and brachytherapy boost with androgen deprivation for treatment of intermediate-risk prostate cancer: Long-term results of CALGB 99809. Cancer 2011; 117(24):5579-5588
  • Lawton CA, Yan Y, Lee WR, Gillin M, Firat S, Baikadi M, Crook J, Kuettel M, Morton G, Sandler H. Long-term results of an RTOG phase II trial (00-19) of external-beam radiation therapy combined with permanent source brachytherapy for intermediate-risk clinically localized adenocarcinoma of the prostate. International journal of radiation oncology, biology, physics 2012; 82(5):e795-e801