Publications and Patents: Year 2002
BADALOVA J, SVOBODOVA M, HAVELKOVA H, VLADIMIROV V, VOJTISKOVA J, ENGOVA J, PILCIK T, VOLF P, DEMANT P, LIPOLDOVA M. Separation and mapping of multiple genes that control IgE level in Laishmania major infected mice. Genes Immun 3:187-195, 2002.
BARBOUR KW, GOODWIN RL, GUILLONNEAU F, WANG Y, BAUMANN H, BERGER FG. Functional diversification during evolution of the murine (1-protease inhibitor family: Role of the hypervariable reactive center loop. Mol Biol Evol 19:718-727, 2002.
BARBOUR KW, WEI F, BRANNAN C, FLOTTE TR, BAUMANN H, BERGER FG. The murine alpha(1)-proteinase inhibitor gene family: polymorphism, chromosomal location, and structure. Genomics 80:515-522, 2002.
BENEKLI M, XIA, Z, DONAHUE KA, FORD LA, PIXLEY LA, BAER MR, BAUMANN H, WETZLER M. Constitutive activity of signal transducer and activator of transcription 3 protein in acute myeloid leukemia blasts is associated with short disease-free survival. Blood 99:252-257, 2002.
BIBER J, JABBOUR S, PARIHAR R, DIERKSHEIDE J, HU Y, BAUMANN H, BOUCHARD P, CALIGIURI M, CARSON W. Administration of two macrophage-derived interferon-gamma-inducing factors (IL-12 and IL-15) induces a lethal systemic inflammatory response in mice that is dependent on natural killer cells but does not require interferon-gamma. Cell Immunol 216:31, 2002.
BLANCHARD F, KINZIE E, WANG Y, DUPLOMB L, GODARD A, HELD WA, ASCH BB, BAUMANN H. FR901228, an inhibitor of histone deacteylases, increases the cellular responsiveness to IL-6 type cytokines by enhancing the expression of receptor proteins. Oncogene 21:6264-6277, 2002.
BLANCHARD F, RUSINIAK ME, SHARMA K, SUN X, TODOROV I, CASTELLANO MM, GUTIERREZ C, BAUMANN H, BURHANS WC. Targeted destruction of DNA replication protein cdc6 by cell death pathways in mammals and yeast. Mol Cell Biol 13:1536-1549, 2002.
BODNAR JS, CHATTERJEE A, CASTELLANI LW, ROSS DA, OHMEN J, CAVALCOLI J, WU C, DAINS CM, CATANESE J, CHU M, SHETH SS, CHARUGUNDLA K, DEMANT P, WEST DB, DE JONG P, LUSIS AJ. Positional cloning of the combined hyperlipidemia gene Hyplip1 Nat Genet 30:110-116, 2002.
BURHANS WC, BLANCHARD F, BAUMANN H. Origin licensing and programmed cell death: a hypothesis. Cell Death Differ 9:870-872, 2002.
CHADHA KC. U.S. Patent 6,475,389. A method for detection of PSMA in the sera of prostate cancer patients. Awarded 11-05-02.
COLINAYO VV, QIAO JH, DEMANT P, KRASS K, LUSIS AJ, DRAKE TA. Genetic characterization of the Dyscalc locus. Mamm Genome 13(6):283-8, 2002.
FENG L, NOVAK EK, HARTNELL LM, BONIFACIO JS, COLLINSON LM, SWANK RT. The Hermansky-Pudlak syndrome 1 (HPS1) and 2 (HPS2) genes independently contribute to the production and function of platelet dense granules, melanosomes and lysosomes. Blood 99:1651-1658, 2002.
GLURICH I, GROSSI S, ALBINI B, HO A, SHAH R, ZEID M, BAUMANN H, GENCO RJ, DE NARDIN E. Systemic inflammation in cardiovascular and periodontal disease: comparative study. Clin Diagn Lab Immunol 9:425-432, 2002.
HOCHEPIED T, WULLAERT A, BERGER F, BAUMANN H, BROUCKAERT P, STEIDLER L, LIBERT C. Overexpression of alpha-1-acid glycoprotein in transgenic mice leads to sensitization to acute colitis. Gut 51:398-404, 2002.
ISAKSEN DE, BAUMANN H, ZHOU B, NIVOLLET S, FARR AG, LEVIN SD, ZIEGLER SF. Uncoupling of proliferation and Stat5 activation in thymic stromal lymphopoietin (TSLP)-mediated signal transduction. J Immunol 168:3288-3294, 2002.
KAWINSKI E, LEVINE E, CHADHA K. Thiophilic interaction chromatography facilitates detection of various molecular complexes of prostate-specific antigen in biological fluids. Prostate 50(3):145-153, 2002.
LIPOLDOVA M, SVOBODOVA M, HAVELKOVA H, KRULOVA M, BADALOVA J, NOHYNKOVA E, HART AAM, SCHLEGEL D, VOLF P, DEMANT P. Mouse genetic model for clinical and immunological heterogeneity of leishmaniasis. Immunogenetics 54:174-183, 2002.
MANLY KF. Computational tools for QTL analysis. In: Genetics of Complex Traits in Model Organisms, John Wiley & Sons, Inc., NY, 2002.
MATSUI S, SAIT S, JONES CA, NOWAK N, GROSS KW. Rapid localization of transgenes in mouse chromosomes using a combined Spectral Karyotyping/FISH technique. Mamm Genome 13:680-685, 2002.
MCGARRY MP, BORCHERS M, NOVAK, E, LEE NA, OHTAKE PJ, LEE JJ, SWANK RT. Pulmonary pathologies in pallid mice result from nonhematopoietic defects. Exp Mol Pathol 72:213-220, 2002.
NAIR MPN, KANDASWAMI C, MAHAJAN S, CHADHA KC, CHAWDA R, NAIR N, KUMAR N, SCHWARTZ SA. The flavonoid, Quecertin, differentially regulates Th-1(IFN-() and TH-2 (IL-4) cytokine gene expression by normal peripheral blood mononuclear cells. Biochim Biophys Acta 1593(1):29-36, 2002.
NGUYEN T, NOVAK EK, KERMANI M, FLUHR J, PETERS LL, SWANK RT, WEI ML. Melanosome morphologies in murine models of Hermansky-Pudlak syndrome reflect blocks in organelle development. J Invest Dermatol 119(5):1156-1164, 2002.
NOVAK EK, GAUTAM R, REDDINGTON M, COLLINSON LM, COPELAND NG, JENKINS NA, MCGARRY MP, SWANK RT. The regulation of platelet dense granules by Rab27a in the ashen mouse, a model of Hermansky-Pudlak and Griscelli syndromes, is granule specific and dependent upon genetic background. Blood 100:128-135, 2002.
OPPEDISANO L, HAINES G, HRABCHAK C, FIMIA G-M, ELLIOTT R, SASSONE-CORSI P, VARMUZA S. The rate of aneuploidy is altered in spermatids from infertile mice. Hum Reprod 17:710-717, 2002.
RUIVENKAMP CAL, VAN WEZEL T, ZANON C, STASSEN APM, VLCEK C, CSIKOS T, KLOUS A, TRIPODIS N, PERRAKIS A, BOERRIGTER L, GROOT PC, LINDEMAN J, MOOI WJ, SCHOLTEN G, DAUWERSE H, PACES V, VAN ZANDWIJK N, VAN OMMEN GJB, DEMANT P. Ptprj is a candidate for the mouse colon cancer susceptibility locus, Scc1, and is frequently deleted in human cancers. Nat Genet 31:295-300, 2002.
RYAN MJ, BLACK TA, MILLARD SL, GROSS KW, HAJDUCZOK G. Endothelin-1 increases calcium and attenuates renin gene expression in As4.1 cells. Am J Physiol Heart Circ Physiol 283(6):H2458-H2465, 2002.
SUZUKI T, LI W, ZHANG Q, KARIM A, NOVAK EK, SVIDERSKAYA EV, HILL SP, BENNETT DC, LEVIN AV, NIEUWENHUIS HK, FONG CT, CASTELLAN C, MITERSKI B, SWANK RT, SPRITZ RA. Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene. Nat Genet 30:321-324, 2002.
TOLOSANO E, FAGOONEE S, HIRSCH E, BERGER FG, BAUMANN H, SILENGO L, ALTRUDA F. Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double null mice after acute hemolysis. Blood 100(12):4201-4208, 2002.
ZHANG Q, LI W, NOVAK EK, KARIM A, MISHRA VS, KINGSMORE SF, ROE BA, SUZUKI T, SWANK RT. The gene for the muted (mu) mouse, a model for Hermansky-Pudlak syndrome, defines a novel protein which regulates vesicle trafficking. Hum Mol Genet 11:697-706, 2002.
ZHANG Q, ZHEN L, LI W, NOVAK EK, COLLINSON, LM, JANG EK, HASLAM R, ELLIOTT RW, SWANK RT. Cell-specific abnormal prenylation of Rab proteins in platelets and melanocytes of the gunmetal mouse. Br J Haematol 117(2):414-423, 2002.


