Title Correlation of Deuterated Phenanthrene Metabolism with Bronchoepitheial Dysplasia and Metaplasia in Smokers at High Risk for Lung Cancer
Principal Investigator Alex Adjei, MD PhD
Study Number 194611
The purpose of this study is to see if how an individual processes deuterated phenanthrene can help predict who is at higher risk of developing abnormalities that can be detected with bronchoscopy and therefore may be a higher risk of developing tobacco smoke-related lung cancer.
Previous aerodigestive tract cancer
Currently attempting to cut down or quit smoking
Major medical co-morbidities, for example, renal dysfunction, heart failure, and diabetes, to be adjudicated by the study physicians
Pregnant women, women intending to become pregnant, or women who are breast feeding