Ultrasensitive PSA Variations with Salivary Gland Stimulation in Men without Prostates
Title Ultrasensitive PSA Variations with Salivary Gland Stimulation in Men without Prostates
Principal Investigator James Mohler, MD
Study Number 188610
PhaseNT
Summary Patients will be identified at a regular clinic visit. Patients in group B will have a fasting blood draw to measure PSA included with their standard laboratory testing. To stimulate the salivary gland, each patient will suck on a sour lemon drop for approximately 5 minutes. One additional serum sample will be drawn approximately 1-2 hours later. Thus the study will involve only one additional blood draw for each patient.
Eligibility
- Study Group A: Patients with pathologically proven adenocarcinoma of the prostate who have undergone radical prostatectomy greater than or equal to 18 months prior and who are followed at RPCI with a minimum of 3 postoperative PSA measurements, all of which are undetectable.
- Study Group B: Patients who have undergone radical cystoprostatectomy for bladder cancer and have no pathologic evidence of prostate cancer.
