Preparing for Your Biopsy

There is no preparation for this test, although some doctors will ask that you use an enema before the test to empty your rectum of stool. Tell your doctor if you have any allergies, especially to antibiotics.

The Day of Your Biopsy

The procedure usually takes about 15-25 minutes.

• You will be asked to lie on your left side to allow for easier insertion of the rectal probe.
• The probe will be coated with a clear lubricating jelly to allow for easier insertion into the rectum.
• The technician will adjust the console on the ultrasound machine to get a baseline for normal prostate tissue.
• When the sensor is put into the rectum, you will feel some pressure that resembles the feeling you have before a bowel movement.
• Imaging is usually begun at the base of the bladder, as the probe is rotated to provide a full picture of the prostate.

Several small biopsies will be taken through the wall of your rectum. The doctors will generally need to take up to 14 biopsies, depending on your condition. These biopsies will sample your prostate and biopsy any suspicious areas seen.

After the Procedure

• After the biopsy, you will be given 2 days' worth of antibiotics. Your first dose will be given at the time of the procedure.
• There is minimal amount of discomfort associated with the biopsy.  Some urologists use local anesthesia that may decrease discomfort in some men.
• There is usually some ongoing bleeding from your rectum and some blood in your urine, though this is usually very small and goes away within a few days.
• Almost all men have bloody ejaculate for 3 to 6 weeks after a biopsy.
• It is important that you take your antibiotics as directed until they are completed.

Call your doctor if you experience:

• Fever of 100.4° or higher, or chills
• Ongoing or excessive bleeding from your rectum