The Transgenic and Gene Targeting Facility at Roswell Park asks investigators that generate mice or mutant ES cells via our facility to do the following:

1) email a citation of the paper and send a reprint to the Facility Assistant, Aimee Stablewski (aimee.stablewski@roswellpark.org)

2) Acknowledge the facility's NCI-funded Cancer Center Support Grant: CA016056

Thank you

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The following papers have been published since the Gene Targeting & Transgenic Resource was initiated as a core facility in 1999:

Appenheimer MM, Huang RY, Chandrasekaran EV, Dalziel M, Hu YP, Soloway PD, Wuensch SA, Matta KL, Lau JT. Biological contribution of P1 promoter-mediated expression of ST6GalI sialyltransferase. Glycobiology 2003. Aug; 13(8):591-600.

Bigg HF, Morrison CJ, Butler GS, Bogoyevitch MA, Wang Z, Soloway PD, Overall CM. Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase a via efficient inhibition of membrane type 1-matrix metalloproteinase. Cancer Res 61:3610-3618, 2001

Chervinsky DS, Lam DH, Melman MP, Gross KW, Aplan PD. SCID Thymocytes with TCRƒÒ gene rearrangements are targets for the oncogenic effect of SCL and LMO1 transgenes. Cancer Res 61:6382-6387, 2001.

Chervinsky DS, Zhao XF, Lam DH, Ellsworth M, Gross KW, Aplan PD. Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient mice. Mol Cell Biol 19:5025-35, 1999

Fitzpatrick GV, Soloway PD, Higgins MJ. Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1. Nature Genetics In Press, 2002.

Herman, H., M. Lu, M. Anggraini, A. Sikora, Y. Chang, B.-J. Yoon, and P.D. Soloway, Trans-Allele Methylation and Paramutation-like Effects In Mice. Nature Genetics, 2003. 34: p.199-202.

Hernandez-Barrantes S, Shimura Y, Soloway PD, Sang QA, Fridman R. Differential roles of TIMP-4 and TIMP-2 in Pro-MMP-2 activation by MT1-MMP. Biochem Biophys Res Commun 281:126-130, 2001.

Jones CA, Hurley MI, Black TA, Kane CM, Pan L, Pruitt SC, Gross KW. Expression of a renin/GFP transgene in mouse embryonic, extra-embryonic, and adult tissues. Physiol Genomics 4:75-81, 2000.

Matsui S, Sait S, Jones CA, Nowak N, Gross KW. Rapid localization of transgenes in mouse chromosomes using a combined Spectral Karyotyping/FISH technique. Mammalian Genome, In Press.

Pruitt SC, Bussman A, Natoli TA, Heinaman R. Neural and anterior-posterior determinants of Pax3 expression. Development, Submitted.

Wang Z, Juttermann R, Soloway PD. TIMP-2 is required for efficient activation of proMMP-2 in vivo. J Biol Chem 275:26411-5, 2000.

Yoon B-J, Herman H, Sikora A, Smith LT, Plass C, and Soloway PD. Regulation of DNA methylation of Rasgrf1. Nature Genet 30:92-96, 2002.

Young JE, Vogt T, Gross KW, Khani SC. A short highly active photoreceptor-specific enhancer/promoter region upstream of the human rhodopsin kinase gene. Invest. Opthamol. Vis. Sci 2003 Sep; 44(9): 4076-85.

Zhao, H., M.M. Bernardo, P. Osenkowski, A. Sohail, D. Pei, H. Nagase, M. Kashiwagi, P.D. Soloway, Y.A. DeClerck, and R. Fridman, Differential Inhibition of MT3-MMP and MT1-MMP by TIMP-2 and TIMP-3 regulates Pro-MMP-2 activation. In Press, J Biol Chem, 2003.