Hong, Chi-Chen, PhD

Assistant Member
Department of Cancer Prevention and Control
Roswell Park Cancer Institute
Dr. Hong's research focuses on the role that diet, body weight, and inherited factors play in cancer development and the effect of weight gain on breast cancer survival. Recently she was awarded four grants totaling over a million dollars to analyze weight gain in women with early-stage breast cancer.
Dr. Hong is a member of the American Association for Cancer Research and serves on AACR sub-committees including the Molecular Epidemiology Group and the Women in Cancer Research Group. She is very involved in efforts to enhance the training experience of early-career investigators and serves as a member of the Associate Member Council at AACR, which develop professional advancement programs aimed at graduate students and postdoctoral fellows. She is also the editor of the monthly News & Networking newsletter sent out to all AACR associate member. Dr. Hong is an ad-hoc reviewer for several journals, including Cancer Research, Breast Cancer Research, Cancer Epidemiology, Biomarkers & Prevention, International Journal of Epidemiology, and Obesity. She has authored or co-authored more than 15 journal publications, abstracts or book chapters.
Selected peer-reviewed publications
- Hong C-C, Thompson HJ, Jiang C, Hammond GL, Tritchler D, Yaffe M, Boyd NF. Val158Met Polymorphism in Catechol-O-methyltransferase (COMT) Gene Associated with Risk Factors for Breast Cancer. Cancer Epidemiology Biomarkers Prevention 2003; 9:838-47.
- Hong C-C, Tang B-K, Rao V, Agarwal S, Martin L, Tritchler D, Yaffe M, Boyd NF. Cytochrome P450 1A2 (CYP1A2) activity, mammographic density, and oxidative stress: a cross-sectional study. Breast Cancer Research 2004; 6:R338-351
- Hong C-C, Tang B-K, Hammond GL, Tritchler D, Yaffe M, Boyd NF. Cytochrome P450 1A2 (CYP1A2) activity and risk factors for breast cancer: a cross-sectional study. Breast Cancer Research 2004; 6: R352-365.
- Hong C-C, Thompson HJ, Jiang C, Hammond GL, Tritchler D, Yaffe M, Boyd NF. Association between the T27C polymorphism in the cytochrome P450c17a (CYP17) gene and risk factors for breast cancer. Breast Cancer Research and Treatment 2004; 88:217-230.
- Yang J, Ambrosone C, Hong C, Ahn J, Rodreguez C, Thun M, Calle E. Relationships between polymorphisms in NOS3 and MPO genes, cigarette smoking, and risk of postmenopausal breast cancer. Carcinogenesis 2007; 28:1247-53.
- Hong C-C, Ambrosone C, Ahn J, Chio J-Y, McCullough ML, Stevens VL, Rodriguez C, Thun MJ, Calle E. Genetic variability in iron-related oxidative stress pathways (Nrf2, NQO1, NOS3, and HO1), iron intake, and risk of postmenopausal breast cancer. Cancer Epidemiol Biomarkers Prev, 16: 1784-94, 2007.
- McCann SE, McCann WE, Hong C-C, Marshall JR, Edge SB, Trevisan M, Muti P, Freudenheim JL. Dietary patterns related to glycemic index and load and risk of pre- and postmenopausal breast cancer in the Western New York Exposures and Breast Cancer (WEB) Study. Am J Clin Nutr 2007;86(2):465-471.


