Hahn, Theresa, PhD

Assistant Member and Assistant Professor of Oncology
Department of Medicine
Cancer Prevention and Population Sciences CCSG Program

Theresa Hahn, PhD, joined the Blood and Marrow Transplantation Program at Roswell Park Cancer Institute (RPCI) in 1998 as a doctoral student and was appointed an Assistant Member in the Department of Medicine and Department of Epidemiology in the Division of Cancer Prevention & Population Sciences in 2003.

Dr. Hahn earned her doctoral degree in Epidemiology in 2000 at the State University of New York at Buffalo (UB); completed a Fellowship in Hematologic Oncology/Blood and Marrow Transplant (BMT) in 2003 from the RPCI Graduate Division. She also serves as Clinical Information Director, Hematologic Oncology Program, Data Management Supervisor, BMT Program, and Director of Quality Assurance, BMT Program RPCI.

Her research interests include clinical epidemiology, outcomes research, evidence based medicine, blood and marrow transplantation and infectious disease epidemiology.

Dr. Hahn is a member of several Center for International Blood and Marrow Transplant Research working committees, the American Society for Blood and Marrow Transplantation, the American Society of Hematology, and the American Association of Cancer Research.

Dr. Hahn has authored or co-authored more than 30 journal articles and 40 abstracts. She is an invited journal reviewer for Blood, Bone Marrow Transplantation, and Biology of Blood and Marrow Transplantation; and invited abstract reviewer for American Society of Hematology.

Key publications (*indicates senior author)

Hahn T,* McCarthy PL,* Zhang MZ, Wang D, Arora M, Sobocinski K, Frangoul H, Gale RP, Hale G, Horan J, Isola L, Maziarz RT, van Rood JJ, Gupta V, Halter J, Reddy V, Tiberghien P, Verdonck LF, Bolwell B, Bredeson C, Chen A, Holler E, Litzow M, Russell J, Pavletic S, Barrett AJ, Ringdén O. Risk factors for grade II-IV acute graft-versus-host disease after HLA-identical sibling transplants for adults with leukemia. *First two authors contributed equally. J Clin Oncol in press.

Aggarwal C, Gupta S, Hahn T, Smiley S, Padmanabhan S, McCarthy PL, Battiwalla M. Human Leukocyte Antigen DR4 is associated with inferior progression-free survival following allogeneic hematopoietic stem cell transplantation for lymphoid malignancies. Leuk Lymphoma 2008 (in press).

Oliansky DM, Appelbaum F, Cassileth PA, Keating A, Kerr J, Nieto Y, Stewart S, Stone RM, Tallman MS, McCarthy PL, Hahn T *. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute myeloid leukemia in adults: an evidence-based review. Biol Blood Marrow Transplant 14:137-180, 2008.

Benekli M, Smiley SL, Younis T, Czuczman MS, Hernandez-Ilizaliturri F, Bambach B, Battiwalla M, Padmanabhan S, McCarthy PL, Hahn T *. Intensive conditioning regimen of etoposide (VP-16), cyclophosphamide, and carmustine (VCB) followed by autologous hematopoietic stem cell transplantation for relapsed and refractory Hodgkin Disease: high likelihood of cure at 2 years. Bone Marrow Transplant 41:613-619, 2008. EPub ahead of print Dec 10, 2007.

Yao S, McCarthy PL,Dunford L, Roy D, Brown K, Paplham P, Syta M, Lamonica D, Smiley S, Battiwalla M, Padmanabhan S, Hahn T *. High prevalence of early onset osteoporosis/osteopenia after allogeneic stem cell transplantation and improvement with bisphosphonate treatment. Bone Marrow Transplant 41:393-398, 2008. EPub ahead of print Nov 12, 2007.

Koutros S, Holford T, Hahn T, McCarthy PL, Lantos PM, Risch H, Swede H. Excess diagnosis of non-Hodgkin lymphoma during spring in the USA. Leuk Lymphoma 48(2):357-66,2007. With accompanying commentary: Chang ET, Clarke CA, Glaser SL. Making sense of seasonal fluctuations in lymphoma diagnosis. Leuk Lymphoma 48(2):223-4,2007.

Oliansky DM, Rizzo JD, Aplan PD, Arceci RJ, Leone L, Ravindranath Y, Sanders JE, Smith FO, Wilmot F, McCarthy PL, Hahn T *. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute myeloid leukemia in children: an evidence based review. Biol Blood Marrow Transplant 13:1-25, 2007.

Benekli M, Hahn T, Williams B, Cooper M, Roy H, Wallace P, Stewart C, Bambach B, McCarthy, Jr PL. Orthoclone® OKT3 murine antibody, cyclosporine and methylprednisolone for acute graft-versus host disease prophylaxis in allogeneic bone marrow transplantation. Bone Marrow Transplant 38:365-370, 2006. First Edition Paper prepublished online July 24, 2006.

Hahn T, Wall D, Camitta B, Davies S, Dillon H, Gaynon P, Larson R, Parsons S, Seidenfeld J, Weisdorf D, McCarthy PL. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in adults: an evidence-based review. Biol Blood Marrow Transplant 12:1-30, 2006.

Battiwalla M, Hahn T, Radovich M, Roy H, Wahab A, Duman E, Bakwa R, Becker J, Padmanabhan S, McCarthy PL. Human Leukocyte Antigen (HLA) DR15 is associated with reduced incidence of acute GVHD in HLA-matched allogeneic transplants but does not impact chronic GVHD incidence. Blood 107:1970-1973, 2006. First Edition Paper prepublished online November 10, 2005.

Hahn T, Wall D, Camitta B, Davies S, Dillon H, Gaynon P, Larson R, Parsons S, Seidenfeld J, Weisdorf D, McCarthy PL. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in children: an evidence-based review. Biol Blood Marrow Transplant 11:823-861, 2005.

Iyer RV, Hahn T, Roy HN, Battiwalla M, Cooper M, Anderson B, Paplham P, Brown K, Bambach B, Segal BH, McCarthy PL. Long term use of oral beclomethasone dipropionate for the treatment of gastrointestinal graft-versus-host disease. Biol Blood Marrow Transplant 11:587-592, 2005.

Hahn T, Benekli M, Wong C, Moysich KB, Hyland A, Michalek AM, Alam A, Baer MR, Bambach B, Czuczman MS, Wetzler M, Becker JL, McCarthy PL. A prognostic model for prolonged event-free survival after autologous or allogeneic blood or marrow transplantation for relapsed and refractory Hodgkin’s disease. Bone Marrow Transplant 35:557-566, 2005.

Hahn T, Alam AR, Lawrence D, Ford L, Baer MR, Bambach B, Bernstein ZP, Czuczman MS, Silva J, Slack JL, Wetzler M, Becker J, McCarthy PL. Thrombotic microangiopathy after allogeneic blood and marrow transplantation is associated with dose-intensive myeloablative conditioning regimens, unrelated donor, and methylprednisolone T-cell depletion. Transplantation 78: 1515-1522, 2004.

McCarthy PL, Kopecky K, Kulikov S, Hahn T, Paltiel O, Drozdova V, Tihnova L, Shmatina N, Von Hoff J, Weinstein H. International Leukemia Diagnostic Working Group (LDWG) verification of acute leukemia (AL) cases in Belarus, Russia and Ukraine after the Chernobyl accident. Leuk Res 28:1273-1280, 2004.

Hahn T, Rondeau C, Shaukat A, Jupudy V, Miller A, Alam AR, Baer MR, Bambach B, Bernstein Z, Chanan-Khan A, Czuczman M, Slack J, Wetzler M, Mookerjee B, Silva J, McCarthy PL. Acute renal failure requiring dialysis after allogeneic blood and marrow transplantation identifies very poor prognosis patients. Bone Marrow Transplant 32: 405-410, 2003.

Hahn T, Benekli M, Shafi F, Quereshi A, Alam AR, Bernstein ZP, Chanan-Khan AA, Czuczman MS, Becker JL, McCarthy PL. The effects of rituximab on peripheral blood stem cell mobilization for autologous stem cell transplantation. Bone Marrow Transplant 32: 139-43, 2003.

Hahn T, Bunworasate U, George MC, Bir AS, Chinratanalab W, Alam AR, Bambach B, Baer MR, Slack JL, Wetzler M, Becker JL, McCarthy PL. Use of non-volume reduced (un-manipulated after thawing) umbilical cord blood stem cells for allogeneic transplantation results in safe engraftment. Bone Marrow Transplant 32: 145-50, 2003.

Hahn T, Wingard J, Anderson K, Bensinger W, Berenson J, Brozeit G, Carver J, Kyle R, McCarthy PL, Jr. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of multiple myeloma: an evidence-based review. Biol Blood Marrow Transplant 9:4-37, 2003.

Hahn T, Cummings KM, Michalek AM, Lipman BJ, Segal BH, McCarthy PL. Efficacy of High-Efficiency Particulate Air Filtration in preventing Aspergillosis in immunocompromised patients with hematologic malignancies. Inf Control Hosp Epi 23: 525-31, 2002.

Hahn T, Wolff SN, Czuczman MC, Fisher RI, Lazarus H, Vose J, Warren L, Watt R, McCarthy PL. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of diffuse large cell B-cell non-Hodgkin’s lymphoma: an evidence-based review. Biol Blood Marrow Transplant 7:308-331; 2001.

Simon M, Hahn T, Ford L, Anderson B, Swinnich D, Baer M, Bambach B, Bernstein S, Bernstein Z, Czuczman M, Slack J, Wetzler M, Herzig G, Schriber J, McCarthy PL. Retrospective multivariate analysis of hepatic veno-occlusive disease after blood and marrow transplantation (BMT): possible beneficial use of low molecular weight heparin. Bone Marrow Transplant 27: 627-33, 2001.