Publications:

 

Activity of the Vascular-Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid against Human Head and Neck Carcinoma Xenografts  Mukund Seshadri, Richard Mazurchuk, Joseph A. Spernyak, Arup Bhattacharya,Youcef M. Rustum and David A. Bellnier Neoplasia Vol. 8, No. 7, July 2006, pp. 534 – 542

High Correlation of Whole-Body Red Fluorescent Protein Imaging and Magnetic Resonance Imaging on an Orthotopic Model of Pancreatic Cancer.  Michael Bouvet, Joseph Spernyak, Matthew H. Katz, Richard V. Mazurchuk, Shinako Takimoto, Ralph Bernacki, Youcef M. Rustum, Abdool R. Moossa and Robert M. Hoffman Cancer Res. 2005 Nov 1;65(21):9829-33.

Tumor vascular response to photodynamic therapy and the antivascular agent 5,6-dimethylxanthenone-4-acetic acid: implications for combination therapy. Seshadri M, Spernyak JA, Mazurchuk R, Camacho SH, Oseroff AR, Cheney RT, Bellnier DA. Clin Cancer Res. 2005 Jun 1;11(11):4241-50.

Magnetic resonance imaging of tumor response to chemotherapy. Mazurchuk R, Spernyak JA. Methods Mol Med. 2005;111:381-415.

Chlorophyll-a analogues conjugated with aminobenzyl-DTPA as potential bifunctional agents for magnetic resonance imaging and photodynamic therapy. Li G, Slansky A, Dobhal MP, Goswami LN, Graham A, Chen Y, Kanter P, Alberico RA, Spernyak J, Morgan J, Mazurchuk R, Oseroff A, Grossman Z, Pandey RK Bioconjug Chem. 2005 Jan-Feb;16(1):32-42.

Ventricular size mapping in a transgenic model of schizophrenia. Torres G, Meeder BA, Hallas BH, Spernyak JA, Mazurchuk R, Jones C, Gross KW, Horowitz JM.Brain Res Dev Brain Res. 2005 Jan 1;154(1):35-44.

Lack of microvessels in well-differentiated regions of human head and neck squamous cell carcinoma A253 associated with functional magnetic resonance imaging detectable hypoxia, limited drug delivery, and resistance to irinotecan therapy. Bhattacharya A, Toth K, Mazurchuk R, Spernyak JA, Slocum HK, Pendyala L, Azrak R, Cao S, Durrani FA, Rustum YM. Clin Cancer Res. 2004 Dec 1;10(23):8005-17.

Activated polyamine catabolism depletes acetyl-CoA pools and suppresses prostate tumor growth in TRAMP mice. Kee K, Foster BA, Merali S, Kramer DL, Hensen ML, Diegelman P, Kisiel N, Vujcic S, Mazurchuk RV, Porter CW. J Biol Chem. 2004 Sep 17;279(38):40076-83. Epub 2004 Jul 13.

High-resolution magnetic resonance imaging of the efficacy of the cytosine analogue 1-[2-C-cyano-2-deoxy-beta-D-arabino-pentofuranosyl]-N(4)-palmitoyl cytosine (CS-682) in a liver-metastasis athymic nude mouse model. Wu M, Mazurchuk R, Chaudhary ND, Spernyak J, Veith J, Pera P, Greco W, Hoffman RM, Kobayashi T, Bernacki RJ Cancer Res. 2003 May 15;63(10):2477-82

Magnetic resonance imaging of dense and light non-aqueous phase liquid in a rock fracture. Becker, M., Pelc, M., Mazurchuk, R., and Spernyak, J., Geophys. Res. Lett., 30(12), 1646