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Awwad R, Sergina N, Yang H, Ziober B, Willson J, Zborowska E, Humphrey L, Fan R, Brattain MG, Howell G. The role of TGFa in determining growth factor independence in colon cancer cells. Cancer Res. 63(15):4731-4738, 2003

Bai S, Goodrich D, Thron D, Tecarro E, Obeyesekere M. Theoretical and Experimental Evidence for Hysteresis in Cell Proliferation. Cell Cycle 2:38-44, 2003

Battaglia A, Bernacki RJ, Bertucci C, Bombardelli E, Cimitan S, Ferlini C, Fontana G Guerrini A, Riva A. Synthesis and biological evaluation of 2’-methyl taxoids derived from Baccatin III and 14 beta-OH-Baccatin III 1,14-carbonate. J Med Chem 46(23):4822-4825, 2003

Black JD, Brattain MG, Krishnamurthi SA, Dawson DM, Willson JKV. ErbB family targeting. Current Opinion in Investigational Drugs 4(12): 1451-1454, 2003

Brooks T, Minderman H, O'Loughlin KL, Pera P, Ojima I, Baer MR, Bernacki RJ. Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein and breast cancer resistance protein. Mol Cancer Thera. 2:1195-1205, 2003

Cao PR, Mchugh MM, Melendy T, Beerman TA. The DNA minor groove-alkylating cyclopropylpyrroloindole drugs adozelesin and bizelesin induce different DNA damage response pathways in human colon carcinoma HCT116 cells. Mol Cancer Ther. 2(7):651-659. 2003

Chen Y, Alm K, Vujcic S, Kramer DL, Kee K, Diegelman P, Porter CW. The role of Mitogen-activated protein kinase activation in determining cellular outcomes in polyamine analogue-treated human melanoma cells. Cancer Res. 63(13):3619-3625, 2003

Chen, Y, Kramer DL, Li F, Porter CW. Loss of inhibitor of apoptosis proteins as a determinant of polyamine-analogue-induced apoptosis in human melanoma cells. Oncogene 22(32):4964-4972, 2003

Chen Y, Kramer D, Jell JA, Vujcic S, Porter CW. Small interfering RNA suppression of polyamine analog-induced spermidine/spermine N1-acetyltransferase. Mol Pharm. 64(5):1153-1159, 2003

Chen Y, Vujcic S, Liang P, Diegelman P, Kramer DL, Porter CW. Genomic identification and biochemical characterization of a second spermidine/spermine N1-acetyltransferase. Biochem J. 373:661-667, 2003

DeArmond D, Brattain MG, Jessup JM, Kreisberg J, Malik S, Zhao S, Freeman JW. Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell line. Oncogene 22(49):7781-7795, 2003

Dimitroff CJ, Bernacki RJ, Sackstein R. Glycosylation-dependent inhibition of cutaneous lymphocyte-associated antigen expression: implications in modulating lymphocyte migration to skin. Blood 101(2):602-610, 2003

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Faessel HM, Slocum HK, Rustum YM, Greco WR. Thymidine and hypoxanthine protection patterns of the folic acid-enhanced synergies for synthesis against human ileocecal HCT-8 cells. Int J Oncol. 23(2):401-409, 2003

Freeman KW, Gangula RD, Welm BE, Ozen M, Foster BA, Rosen JM, Ittmann M, Greenberg NM, Spencer DM. Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation. Cancer Res. 63(19):6237-6243, 2003

Frydman B, Porter CW, Maxuitenko Y, Sarkar A, Bhattacharya S, Valasinas A, Reddy VK, Kisiel N, Marton LJ, Basu HS. A novel polyamine analog (SL-11093) inhibits growth of human prostate tumor xenografts in nude mice. Cancer Chemother Pharmacol. 51(6):488-492, 2003

Gangjee A, Yu J, Kisliuk RL, Haile WH, Sobrero G, McGuire JJ. Design, synthesis and biological activities of classical N-{4-[2-(2-amino-4-ethylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid and its 6-methyl derivative as potential dual inhibitors of thymidylate synthase and dihydrofolate reductase and as potential antitumor agents. J Med Chem. 46(4):591-600, 2003

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Goodrich DW. How the Other Half Lives, the Amino-terminal Domain of the Retinoblastoma Tumor Suppressor Protein. J Cell Physiol. 197(2):169-180, 2003

Hanahan D, Lanzavecchia A, Mihich E. Fourteenth Annual Pezcoller Symposium: the novel dichotomy of immune interactions with tumors. Cancer Res. 63(11):3005-3008, 2003

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Ip MM, Masso-Welch PA, Ip C. Prevention of mammary cancer with conjugated linoleic acid: role of the stroma and the epithelium. J Mammary Gland Biol Neoplasia 8(1):103-118, 2003

Kaplan-Lefko PJ, Chen T, Ittmann MM, Barrios RJ, Ayala GE, Huss WJ, Maddison LA, Foster BA, Greenberg NM. Pathobiology of autochthonous prostate cancer in a pre-clinical transgenic mouse model. Prostate 55(3):219-237, 2003

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Liu JS, Kuo SR, Beerman TA, Melendy T. Induction of DNA damage responses by adozelesin in S phase-specific and dependent on active replication forms. Mol Cancer Thera. 2(1):41-47, 2003

Malik SN, Bedolla RG, Hidalgo M, Brattain MG, Kreisberg JI. Immunohistochemical determination of EGFR-tyrosine kinase inhibition in clinical samples. Methods Mol Med. 85:135-140, 2003

Malik SN, Siu LL, Rowinsky EK, deGraffenried L, Hammond LA, Rizzo J, Bacus S, Brattain MG, Kreisberg JI, Hidalgo M. Pharmacodynamic evaluation of the epidermal growth factor receptor inhibitor OSI-774 in human epidermis of cancer patients. Clin Ca Research 9:2478-2486, 2003

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McGuire JJ, Coward JK. Folylpolyglutamate synthetase as a target for therapeutic intervention. (Review Article) Drugs of the Future 28(10):967-974, 2003

McGuire JJ, Haile WH, Valiaeva N, Bartley D, Coward JK. Potent inhibition of human folylpolyglutamate synthetase by a phosphinic acid mimic of the tetrahedral reaction intermediate. Biochem Pharmacol. 65(3):315-318, 2003

Mihich E. Cellular immunity for cancer chemoimmunotherapy – an overview of Symposium-in-Writing (authors: Vesosky B, Hurwitz, Chen Q, Wang, W-C, Evans S, Terando A, Mule J, Mitchell M) Cancer Immunol Immunother. 52(11):661-662, 2003

Muindi JR, Wilson JW, Peng Y, Cappozolli MJ, Johnson CS, Trump DL. A limited sampling method for the estimation of serum calcitriol area under the curve in cancer patients. J Clin Pharm 43(18):894-900, 2003

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Sawhney RS, Sharma B, Humphrey LE, Brattain M. Integrin a2 and extracellular signal-regulated kinase are functionally linked in highly malignant autocrine TGFa driven colon cancer cells. J Biol Chem. 278(22):19861-19869, 2003

Srivastava SK, Xiao D, Lew KL, Hershberger P, Kokkinakis DM, Johnson CS, Trump DL, Singh SV. Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of PC-3 human prostate cancer xenografts in vivo. Carcinogenesis 24(10):1665-1670, 2003

Subhi AL, Diegelman P, Porter CW, Tang B, Lu ZJ, Markham GD, Kruger WD. Methylthioadenosine phosphorylase regulates ornithine decarboxylase by production of downstream metabolites. J Biol Chem. 278(50):49868-49873, 2003

Tan D, Kirley S, Li Q, Ramnath N, Slocum HK, Brooks JS, Wu CL, Zukerberg LR. Loss of cables protein expression in human non-small cell lung cancer: A tissue microarray study. Hum Pathol. 34(2):143-149, 2003

Tan DF, LiQ, DeebG, Ramnath N, Slocum HK, Brooks J, Cheney R, Wiseman S, Anderson T, Loewen G. Thyroid transcription factor-1 expression prevalence and its clinical implications in non-small cell lung cancer: A high-throughput tissue microarray and immunohistochemistry study. Hum Pathol. 34(6):597-604, 2003

Tan DF, Deeb G, Wang JM, Slocum HK, Winston J, Wiseman S, Beck A, Sait S, Anderson T, Nwogu C, Ramnath N, Loewen G. HER-2/neu protein expression and gene alteration in stage I-IIIA non-small-cell lung cancer: A study of 140 cases using a combination of high throughput tissue microarray, immunohistochemistry, and fluorescent in situ hybridization. Diagn.Mol.Pathol. 12(4):201-21, 2003

Tewes M, Schleucher N, Achterrath W, Wilke HJ, Frings S, Seeber S, Harstrick A, Rustum YM, Vanhoefer U. Capecitabine and irinotecan as first-line chemotherapy in patients with metastatic colorectal cancer: results of an extended phase I study dagger. Ann Oncol. 14(9):1442-1448, 2003

Traicoff NL, Periyasamy S, Brattain MG, Grady W, Casey G. Reconstitution of TGF-beta sensitivity in the VACO-411 human colon carcinoma line by somatic cell fusion with MCF-7. J Biomed Sci. 10(2):253-259, 2003

Ujhazy P, Zaleskis G, Mihich E, Ehrke MJ, Berleth ES. Doxorubicin induces specific immune functions and cytokine expression in peritoneal cells. Cancer Immunol Immunother. 52(7):463-472, 2003

Vujcic S, Liang P, Diegelman P, Kramer DL, Porter CW. Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion. Biochemical J. 370:19-28, 2003

Wang YD, Dziegielewski J, Wurtz NR, Dziegielewska B, Dervan PB, Beerman TA. DNA crosslinking and biological activity of a hairpin polyamide-chlorambucil conjugate. Nucleic Acid Research 31(4):1208-1215, 2003

White DB, Slocum HK, Brun Y, Wrzosek C, Greco WR. A new nonlinear mixture response surface paradigm for the study of synergism: a three drug example. Curr Drug Metab. 4(5):399-409, 2003

Wu M, Mazurchuk R, Chaudhary ND, Spernyak J, Veith J, Pera P, Greco W, Hoffman RM, Kobayashi T, Bernacki RJ. High-resolution magnetic resonance imaging of the efficacy of the cytosine analogue 1-[2-C-cyano-2-deoxy-beta-D-arabino-pentofuranosyl]- N4-palmitoyl cytosine (CS-682) in a liver-metastasis athymic nude mouse model. Cancer Res. 63(10):2477-2482, 2003

Wu Q, Dolnick BJ. Detection of thymidylate synthase modulators by a novel screening assay. Mol Pharmacol. 63(1):167-173, 2003

Xiao D, Srivastava SK, Lew K, Zeng Y, Kokkinakis DM, Hershberger P, Johnson CS, Trump DL, Singh SV. Allyl Isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of human prostate cancer cells in culture and in vivo in nude mice by inducing apoptosis and causing G2/M arrest. Carcinogenesis 24(5):891-897, 2003

Zahedi K, Wang ZH, Barone S, Prada AE, Kelly CN, Casero RA, Yokota N, Porter CW, Rabb H. Soleimani M. Expression of SSAT, a novel biomarker of tubular cell damage, increases in kidney ischemia-reperfusion injury. Am J Physiol Renal Physiol. 284(5):F1046-F1055, 2003

Zanker KS, Brentani R, Mihich E. International symposium on new leads in experimental and clinical gene targeting in cancer. J Cancer Res Clin Oncol. 129(4):258-261, 2003

Zhu Y, Roshal M, Li F, Blackett J, Planelles V. Upregulation of survivin by HIV-1 Vpr. Apoptosis 8(1):71-79, 2003