Publications

Key Publications

Kowalski D, Pendyala L, Daignan-Fornier B, Howell SB, Huang RY. Dysregulation of purine nucleotide biosynthesis pathways modulates cisplatin cytotoxicity in Saccharomyces cerevisiae. Mol Pharmacol. 2008 Oct;74(4):1092-100. Epub 2008 Jul 8. [PubMed Abstract]
Huang RY, Kowalski D, Minderman H, Gandhi N, Johnson ES. Small ubiquitin-related modifier pathway is a major determinant of doxorubicin cytotoxicity in S. cerevisiae. Cancer Res 67:765-772, 2007. [PubMed Abstract]
Aladjem MI, Falaschi A, Kowalski D. Eukaryotic DNA replication origins, in DNA Replication & Human Disease, Cold Spring Harbor Lab Press, NY, (ed. DePamphilis, M.L.) pp. 31-62, 2006.
Huang, R, Eddy, M, Vujcic, M, Kowalski, D. Genome-wide screen identifies genes whose inactivation confers resistance to cisplatin in Saccharomyces Cerevisiae. Cancer Res 65:13:5890-5897, 2005. [PubMed Abstract]
Dziegielewska B, Kowalski D, Beerman T. SV40 DNA replication inhibition by the monofunctional DNA alkylator Et743. Biochemistry 43: 14228-14237, 2004. [PubMed Abstract]
Huang Y. and Kowalski D. PATTERNFINDER: combined analysis of DNA regulatory sequences and double-helix stability. BMC Bioinformatics 5: 134, 2004. [PubMed Abstract] [Full text]
Huang Y. and Kowalski, D. WEB-THERMODYN: sequence analysis software for profiling DNA helical stability. Nucleic Acids Res 31: 3819-3821, 2003. [PubMed Abstract] [Full text]
Kowalski D. Checkpoint kinase proteins stabilize DNA replication forks after DNA damage or arrest of fork movement. Chemtracts - DNA Replication, Part I (M. DePamphilis, editor) 15:334-339, 2002. [Invited Commentary] [Full text]
Wang Y, Beerman TA, Kowalski D. Antitumor drug adozelesin differentially affects active and silent origins of DNA replication in yeast checkpoint kinase mutants. Cancer Res 61:3787-3794, 2001. [PubMed Abstract]
Wang Y, Vujcic M, Kowalski D. DNA replication forks pause at silent origins near the HML locus in budding yeast. Mol Cell Biol 21:4938-4948, 2001. [PubMed Abstract]
Vujcic M, Miller CA, Kowalski D. Activation of silent replication origins at ARS elements near the HML locus in budding yeast. Mol Cell Biol 19:6098-6109, 1999. [PubMed Abstract]
Miller CA, Umek RM, Kowalski D. The inefficient replication origin from yeast ribosomal DNA is naturally impaired in the ARS consensus sequence and in DNA unwinding. Nucleic Acids Res 27:3921-3930, 1999. [PubMed Abstract]
Lin S. and Kowalski D. Functional equivalency and diversity of cis-acting elements among yeast replication origins. Mol Cell Biol 17: 5473-5484, 1997. [PubMed Abstract]
Huang R-Y. and Kowalski D. A DNA unwinding element and an ARS consensus comprise a replication origin within a yeast chromosome. EMBO J 12: 4521-4531, 1993. [PubMed Abstract]