| Stage |
Phase |
Principal Investigator |
Study prefix |
Study number |
Title (click hyperlink for more information) |
| Pilot | Swati Kulkarni, MD | I | 99507 | A Pilot Study of Flaxseed vs Aromatase Inhibitor Between Biopsy and Surgery: Breast Tumor Characteristics and Prognosis |
| II | Ellis Levine, MD | PH | 134408 | A Double-Blind, Randomized Phase 2b Study of Sorafenib Compared to Placebo When Administered in Combination with Chemotherapy for Patients with Locally Advanced or Metastatic Breast Cancer That has Progressed During or After Bevacizumab Therapy |
| Pilot | Swati Kulkarni, MD | I | 81906 | A Study Evaluating the Effect of Flaxseed on Biomarkers of Breast Cancer Risk |
| III | Ellis Levine, MD | NCG | 104707 | (SWOG S0500) A Randomized Phase III Trial to Test the Strategy of Changing Therapy Versus Maintaining Therapy for Metastatic Breast Cancer Patients Who Have Elevated Circulating Tumor Cell Levels at First Follow-Up Assessment |
| I-III | III | Ellis Levine, MD | NCG | 78106 | (IBCSG 25-02 Tamoxifen and Exemestane Trial) A Phase III Trial Evaluating the Role of Exemestane Plus GnRH Analogue as Adjuvant Therapy for Premenopausal Women with Endocrine Responsive Breast Cancer |
| III | Ellis Levine, MD | NCG | 82606 | (ECOG PACCT-1) Program for the Assessment of Clinical Cancer Tests (PACCT-1): Trial Assigning IndividuaLized Options for Treatment: The TAILORx Trial |
| I-III | Ellis Levine, MD | NCG | 81106 | (SWOG S0307) Phase III Trial of Biphosphonates as Adjuvant Therapy for Primary Breast Cancer |
| N/A | HongC | I | 53005 | Women's Health After Breast Cancer Study |
| III | Ellis Levine, MD | NCG / CALGB | 101207 | (CALGB 40302) Endocrine Therapy With or Without Inhibition of EGF and HER2 Growth Factor Receptors: A Randomized, Double-Blind, Placebo-Controlled Phase III Trial of Fulvestrant With or Without Lapatinib (GW572016) for Postmenopausal Women with Hormone Receptor Positive Advanced Breast Cancer |
| N/A | III | Ellis Levine, MD | NCG | 14703 | (CTSU IBCSG 24-02): A Phase III Trial Evaluating the Role of Ovarian Function Suppression and the Role of Exemestane as Adjuvant Therapies for Premenopausal Women with Endocrine Responsive Breast Cancer |
| N/A | Survey | Stephen Edge, MD | NCG / CALGB | 14103 | (CALGB 369901) Observational Cohort Study: Chemotherapy Decisions in Women Age 65 or Older with Operable, Newly Diagnosed Breast Cancer |
| III | | NCG | 124707 | A Double-Blind Phase III Trial of Doxorubicin and Cyclophosphamide followed by Paclitaxel with Bevacizumab or Placebo in Patients with Lymph Node Positive and High Risk Lymph Node Negative Breast Cancer |
| II | Grace Dy, MD | PH | 127408 | A Phase 2 Study to Assess the Safety and Preliminary Efficacy of ARRY-334543 with Capecitabine or Lapatinib with Capecitabine in Patients with Advanced Breast Cancer Following a Phase 1 Lead-In to Assess the Safety of ARRY-334543 with Capecitabine in Patients with Advanced Cancer |
| III | Ellis Levine, MD | NCG | 146708 | (CALGB 40601) Randomized Phase III Trial of Paclitaxel Combined with Trastuzumab, Lapatinib, or Both as Neoadjuvant Treatment of HER2-Positive Primary Breast Cancer |
| III | Stephen Edge, MD | NCG | 150809 | (CTSU NSABP B-43) A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma in Situ Resected by Lumpectomy |
| III | Ellis Levine, MD | NCG | 157709 | (CALGB 40502) A Randomized Phase III Trial of Weekly Paclitaxel Compared to Weekly Nanoparticle Albumin Bound Nab-Paclitaxel or Ixabepilone Combined with Bevacizumab as First-Line Therapy for Locally Recurrent or Metastatic Breast Cancer |
| N/A | III | Ellis Levine, MD | NCG / CALGB | 42704 | (CALGB 40401) Phase III Trial of LHRH Analog Administration During Chemotherapy to Reduce Ovarian Failure Following Chemotherapy in Early Stage, Hormone-Receptor Negative Breast Cancer |
| III | Ellis Levine, MD | NCG | 130808 | A Randomized, Multi-Centre, Open-Label, Phase III Study of Adjuvant Lapatinib, Trastuzumab, Their Sequence and Their Sequence in Patients with HER2/ErB2 Positive Primary Breast Cancer |
| NT | Tracey OConner, MD | I | 146508 | Correlation of Doxorubicin and Doxorubicinal Levels with Carbonyl Reductase Genotypes in Patients Receiving Doxorubicin for Treatment of Breast Cancer |
| III | Ellis Levine, MD | NCG | 128908 | E1105: A Randomized Phase III Double-Blind Placebo-Controlled Trial of First-line Chemotherapy and Trastuzumab With or Without Bevacizumab for Patients with HER-2/NEU Over-expressing Metastatic Breast Cancer (CLOSED with TX) |
| Survey | Ellis Levine, MD | NCG / CALGB | 69205 | (CALGB 70301/CTSU C7031) Quality of Life, Employment and Informal Care Cost Analysis in Women Receiving Adjuvant Chemotherapy for Breast Cancer with 0-3 Positive Axillary Lymph Nodes. (CLOSED w/FOLLOW UP) |
| | Ellis Levine, MD | NCG | 136308 | (ANZ 0701 Co-SOFT) Cognitive Function Substudy:Investigating Cognitive Function for Patients Participating in the SOFT Trial in Selected Centers |
| III | Ellis Levine, MD | NCG | 101907 | (NSABP B-42) A Clinical Trial to Determine the Efficacy of Five Years of Letrozole Compared to Placebo in Patients Completing Five Years of Hormonal Therapy Consisting of an Aromatase Inhibitor (AI) or Tamoxifen Followed by an AI in Prolonging Disease-Free Survival in Postmenopausal Women with Hormone Receptor Positive Breast Cancer |