| Stage |
Phase |
Principal Investigator |
Study prefix |
Study number |
Title (click hyperlink for more information) |
| I | Adekunle Odunsi, MD PhD | PH | 144908 | (MDX1105-01) Phase I, Open-Label, Multicenter, Dose-Escalation, Multidose Study of MDX-1105 Administered Every 14 Days in Subjects with Selected Advanced or Recurrent Solid Tumors |
| I | Michael Wong, MD PhD FRCPC | I | 126408 | An Open Label Phase I Dose Finding Study Of TRC105 In Patients With Advanced Or Metastatic Solid Cancer For Whom Curative Therapy Is Unavailable |
| I | Alex Adjei, MD PhD | I | 150009 | A Phase I Dose Escalation Study of ARQ197 Administered in Combination with Sorafenib in Adult Patients with Advanced Solid Tumors |
| I | Grace Dy, MD | PH | 99007 | (CA187004) A Phase I Study to Determine the Safety, Pharmacokinetics and Pharmacodynamics of BMS-690514 in Combination with Paclitaxel and Carboplatin for Patients with Advanced or Metastatic Solid Tumors |
| I | Marwan Fakih, MD | I | 55305 | A Phase I Study of Suberoylanilide Hydroxamic Acid (SAHA, Vorinostat) in Combination with 5-Fluorouracil, Leucovorin and Oxaliplatin (FOLFOX) in Patients with Colorectal Cancer and other Solid Tumors(NCI#6789) |
| Advanced Malignancies | I | Renuka Iyer, MD | I | 23204 | An Open-Label, Dose Escalation study of Paricalcitol (Zemplar TM) {19-NOR-1 ALPHA, 25-(OH)2 D2] in Combination with Gemcitabine (Gemzar) [2',2' Diflurodeoxycytidine] in patients with advanced Malignancies |
| I | Wen Wee Ma, MD | PH | 135008 | (A7471004) Phase I Targeted Combination Trial of PF-00299804 and CP-751,871 in Patients with Advanced Solid Tumors |
| I | Alex Adjei, MD PhD | PH | 119407 | A Multi-Center Phase 1, Dose-Escalation Trial to Determine the Safety and Pharmacokinetics/Pharmacodynamics of RDEA119, a MEK Inhibitor, in Advanced Cancer Patients |
| I | Wen Wee Ma, MD | I | 137508 | Phase I Dose Escalation Study of Gemcitabine and ON 01910.Na in Patients with Advanced or Metastatic Solid Tumors |
| Advanced | I | Roberto Pili, MD | I | 150609 | ( C11981/1047/ON/US) An Open-Label Study to Determine the Maximum Tolerated Oral Dose of the Kinase Inhibitor CEP-11981 in Patients with Advanced Cancer |
| I | Wen Wee Ma, MD | I | 154309 | (XL518-001) A Phase I Dose-Escalation of the Safety and Pharmacokinetics of GDC-0973/XL518 Administered Orally Daily to Subjects with Solid Tumors |
| I | Alex Adjei, MD PhD | I | 149609 | (VEG105430) An Open-Label, Phase 1b Study to Assess the Long-Term Safety Profile of Pazopanib in Cancer Patients |
| Ib | Grace Dy, MD | I | 157909 | (SHH4610g) A Phase 1b, Open-Label, Dose-Scheduling Study of HedgehogPathway Inhibitor GDC-0449 in Patients with Locally Advanced or Metastatic Solid Tumors That Are Refractory to Standard Therapy or for Whom No Standard Therapy Exists |