Molecular & Cellular Biophysics and Biochemistry
Graduate PROGRAM
“Better cancer therapies through knowledge and innovation.”
The current understanding of cancer as a disease and clinical approaches to treating cancer have made enormous gains in the past couple of decades. This was made possible by tremendous technological advances that delivered unparalleled capabilities and a wealth of knowledge to the biomedical field. In our research, we use the insights into stress response mechanisms in normal and cancerous cells to improve the outcomes of cancer treatment, including the design of novel anti-cancer therapies, and amelioration of the side effects and enhancement of efficacy of the available ones.
Our faculty members maintain a strong tradition of technological innovation, which leads to the establishment of new concepts in treatment and diagnosis of the disease, and to the discovery of prospective therapeutic targets and potent chemotherapeutic agents. Our students are exposed to a challenging curriculum delivered by a team of experts from RPCI and other institutions and conduct high-impact research in several crucial and interlinked areas of modern oncology:
- Through the studies of signal transduction and gene regulation we expand the knowledge of the origins of cancer and the therapeutic responses of the disease.
- Gene and drug discovery capitalizes on our expertise in biology of normal and tumor cells in order to identify and characterize therapeutic targets and chemotherapeutic agents.
- Biophysical therapies intensively studied by our scientists include radiation, thermal and photodynamic (PDT) therapies. PDT has been developed at Roswell Park Cancer Institute and our Institution remains the world leader in research and clinical applications of this technology.
- Our teams of biophysicists, chemists, and molecular biology and nanotechnology experts develop and optimize cancer targeting strategies for drug delivery, as well as for imaging and diagnostic purposes.
Successful integration of basic and clinical research remains the main strength of Roswell Park Cancer Institute. A network of close collaborations with clinicians and industrial scientists expedites the transition of relevant findings “from bench to bedside” and provides a comprehensive and versatile training experience for our students.


